Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Unable to load your collection due to an error, Unable to load your delegates due to an error. Accessed Sept. 7, 2022. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). official website and that any information you provide is encrypted Consult your pharmacist or local waste disposal company. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. If you have ever had an allergic reaction to a medicine. Do not let anyone else take your medication. Many herbal supplements can interact with prescription drugs. Isosorbide mononitrate: isosorbide mononitrate. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Otherwise, call a poison control center right away. Isosorbide may cause other side effects. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Store in a cool, dry place, away from direct heat and light. Other medications may be prescribed by your doctor for these conditions. You can take your doses either before or after meals. Talk to your pharmacist for more details. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. It might help to take isosorbide mononitrate and dinitrate after meals. What conditions does Isosorbide Mononitrate treat? Natural Medicines. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Your health care provider and pharmacist can help you stay away from unsafe interactions. Please see a good cardiologist, get admitted, get checked thoroughly. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Epub 2006 Mar 22. Am J Ther. Many people using this medication do not have serious side effects. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Do not store in the bathroom. Take the container with you, even if it is empty. The Swedish Multicentre Group. Do not take two doses together to make up for a missed dose. include protected health information. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. 46 ratings on Drugs.com. St. John's wort. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Bethesda, MD 20894, Web Policies The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. Accessed Sept. 7, 2022. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Saper RB. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Natural Medicines. Data were assessed for carryover and time effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Liperoti R, et al. Do not take more or less of it or take it more often than prescribed by your doctor. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Some of these interactions can be life-threatening. The extended-release tablet usually is taken once daily in the morning. Keep all medicines out of the reach and sight of children. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Results: It is components of vit. Compare a few possible alternatives below. These side effects may go away during treatment as your body adjusts to the medicine. This site needs JavaScript to work properly. Learn to reduce stress through mindful living. Licorice. If you become pregnant while taking isosorbide, call your doctor. Isosorbide mononitrate helps to prevent angina chest pain from developing. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. [2] It is taken by mouth. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Natural Medicines. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Mayo Clinic; 2021. . May also be prescribed off label for Esophageal Spasm. Isosorbide mononitrate is very similar to isosorbide dinitrate. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). It might help to keep the room cool and use a fan. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Herbal supplements can strongly affect the body. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Daily headaches are a common side effect. Danshen. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. 55 ratings on Drugs.com. It is used to treat and prevent a wide range of different conditions. Keep this medication in the container it came in, tightly closed, and out of reach of children. FOIA The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. All rights reserved. Side effects : headache, mild dizziness Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Dehydration in Buspar, how severe and when it was recovered? Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Ask your doctor before using aspirin together with alcohol. AskMayoExpert. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Integrative medicine (complementary and alternative medicine). It will not treat an angina attack that has already begun. This drug may make you dizzy. you should know that you may experience headaches every day during your treatment with isosorbide. You need to take it every day in order for it to work. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Talk to your doctor about the possible risks of using this medication for your condition. Take care, thanks. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Seek alternatives to the CYP3A4 substrate when possible. With any medication, there are risks and benefits. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). 2023 Lybrate, Inc. All rights reserved. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Highly clinically significant. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Normal ecg doesn't rule out heart disease. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Diabetes treatment: Can cinnamon lower blood sugar? Journal of the American College of Cardiology. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Clipboard, Search History, and several other advanced features are temporarily unavailable. It is unknown if this medication passes into breast milk. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Discuss the risks and benefits with your doctor. Natural remedies for depression: Are they effective? Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). It has a very short duration of action and may not be suitable for some people. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Isosorbide controls chest pain but does not cure coronary artery disease. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. A very serious allergic reaction to this drug is rare. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Is not subject to the Controlled Substances Act. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The effects of this exposure on a nursing infant are unknown. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Herbal supplements are natural, so they must be safe, right? No, that's not true all the time. We comply with the HONcode standard for trustworthy health information. Coenzyme Q-10 Natural Medicines. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. It is in the nitrate class of drugs. Take your next dose at the regular time. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Portions of this document last updated: Feb. 01, 2023. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. US residents can call their local poison control center at 1-800-222-1222. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. The most common side-effect is headache. Isosorbide mononitrate. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. GoodRx works to make its website accessible to all, including those with disabilities. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Isosorbide mononitrate belongs to the group of medicines called nitrates. This is called a medicine interaction. Accessed Sept. 7, 2022. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Call your doctor for medical advice about side effects. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Try our Symptom Checker Got any other symptoms? Evening primrose. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. https://naturalmedicines.therapeuticresearch.com. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Please enable it to take advantage of the complete set of features! Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. https://naturalmedicines.therapeuticresearch.com. Which drugs or supplements interact with isosorbide mononitrate? The extended-release capsule usually is taken once daily. Isosorbide is in a class of medications called vasodilators. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. This site complies with the HONcode standard for trustworthy health information: verify here. Accessed Sept. 7, 2022. This should pass after a few days. This medication belongs to a class of drugs known as nitrates. . information is beneficial, we may combine your email and website usage information with All rights reserved. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention.
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